Coumarins of Peucedanum baicalense and cytotoxic activity of some isolated coumarins
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چکیده
منابع مشابه
Antifungal activity of coumarins.
The antifungal activity of 40 coumarins was tested against the fungal strains: Candida albicans (ATCC 14053), Aspergillus fumigatus (ATCC 16913) and Fusarium solani (ATCC 36031), using the broth microdilution method. Osthenol showed the most effective antifungal activity among all the compounds tested, with a MIC value of 125 microg/ml for Fusarium solani and 250 micro/ml for Candida albicans a...
متن کاملAntibacterial activity of coumarins.
The antibacterial activity of coumarin per se and other 45 coumarin derivatives was tested against strains of Bacillus cereus MIP 96016, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Staphylococcus aureus ATCC 25923. The inhibitory effects of coumarins were affected by their substitution patterns. Osthenol (44) showed the most effective antibacterial activity against Gram-...
متن کاملSynthesis of Functionalized Coumarins
The synthesis of functionalized 2-oxo-2H-coumarin derivatives has been studied by a one-pot reaction of o-hydroxybenzaldehyde, ethyl 2-bromoacetate and triphenylphosphine in the presence of catalytic amount of triethyl amine in EtOAc, water or under solvent free conditions. We have found the best results obtained under solvent free condition.
متن کاملPHOTOREACTICITY (365 nm) OF SOME COUMARINS
The Authors have studied the capacity to photoreact with native DNA and r-RNA using six coumarins and four 4',5'-dihydro-furo-coumarins. Six of these substances have shown a definite photoreactivity both with DNA and r-RNA, even if in a very much lower extent in respect to that of skin-photosensitizing furocoumarins. The low capacity to photoreact with nucleic acids of these substances is discu...
متن کاملSynthesis and biological activities of some new fluorinated coumarins and 1-aza coumarins.
A series of new fluorinated coumarins and 1-aza coumarins have been synthesized and the presence of fluorine in these molecules and its effect on their anti-microbial, anti-inflammatory and analgesic activities are discussed. The results of bioassay showed that these newly synthesized compounds containing fluorine exhibit moderate analgesic and excellent anti-inflammatory and potential anti-bac...
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ژورنال
عنوان ژورنال: Mongolian Journal of Chemistry
سال: 2014
ISSN: 2414-0082,2226-6739
DOI: 10.5564/mjc.v13i0.155